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Walk the Even Hospital Database by book and chapter — the raw source passages that ground Ask, DDx, and the rest.
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©2013 UpToDate ® Print Email Avoiding ICH during warfarin therapy Elderly patients and those with intrinsic cerebrovascular disease are at high risk. Keep INRs ≤3.0. Warfarin combined with aspirin should be used with caution in elderly patients and those with cerebrovascular disease and the benefits versus risks carefully weighed. Modest blood pressure lowering profoundly reduces ICH risk; systolic blood pressure should optimally be lowered to <140 mmHg. Reproduced with permission from: Hart RG, Tonarelli SB, Pearce LA. Avoiding central nervous system bleeding during antithrombotic therapy: Recent data and ideas. Stroke 2005; 36:1588. Copyright © 2005 Lippincott Williams & Wilkins.