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©2013 UpToDate ® Print Email Expected values of BAL fluid constituents in healthy never smokers Variable Mean ± SEM 5th percentile* 95th percentile • Percent recovery of lavagate 63.4 ± 1.1 40.8 80.3 Total cells, 10 6Δ 18.1 ± 1.9 5.2 33.1 Total cells/mL, 10 4Δ 12.9 ± 2.0 3.1 35.1 Macrophages, percent Δ 85.2 ± 1.6 54.6 97.1 Macrophages/mL, 10 4Δ 9.9 ± 0.8 2.7 27.5 Lymphocytes, percent Δ 11.81 ± 1.1 1.9 34.3 Lymphocytes/mL, 10 4Δ 1.49 ± 0.25 0.2 4.9 Neutrophils, percent Δ 1.6 ± 0.7 0.0 3.1 Neutrophils/mL, 10 4Δ 1.2 ± 1.1 0.0 0.4 Eosinophils, percent Δ 0.19 ± 0.06 0.0 1.1 Eosinophils/mL, 10 4Δ 0.02 ± 0.007 0.0 0.2 T cells, percent ◊ 70.27 ± 3.56 25.6 94.9 T-helper cells, percent ◊ 44.4 ± 3.71 7.6 83.5 T-suppressor cells, percent ◊ 20.73 ± 2.17 6.6 49.4 Helper/suppressor ratio ◊ 2.61 ± 0.29 0.5 6.4 B cells, percent ◊ 3.23 ± 0.85 0.0 17.1 IgG, mcg/mL § 5.92 ± 0.48 1.6 14.5 IgA, mcg/mL § 6.22 ± 0.60 1.1 15.3 IgM, mcg/mL § 0.20 ± 0.019 0.03 0.6 Albumin, mcg/mL § 34.23 ± 1.67 15.7 59.3 Total protein, mcg/mL § 78.24 ± 4.04 39.5 140.7 BAL: bronchoalveolar lavage. * 5th percentile of the study population. • 95th percentile of the study population. Δ n = 77. ◊ n = 30. § n = 76. Data from: BAL Cooperative Group. Am Rev Respir Dis 1990; 141:S169 (BAL Cooperative Group, 1990 #261). Expected values of BAL fluid constituents in healthy former smokers Variable Mean ± SEM 5th percentile* 95th percentile • Percent recovery of lavagate 62.3 ± 1.4 42.6 80.4 Total cells, 10 6Δ 20.01 ± 1.5 8.7 44.6 Total cells/mL, 10 4Δ 13.9 ± 1.1 5.2 31.4 Macrophages, percent Δ 86.5 ± 1.4 66.6 97.0 Macrophages/mL, 10 4Δ 11.9 ± 0.9 4.0 29.0 Lymphocytes, percent Δ 11.5 ± 1.2 2.0 29.3 Lymphocytes/mL, 10 4Δ 1.69 ± 0.31 0.1 5.6 Neutrophils, percent Δ 2.1 ± 0.5 0.0 8.4 Neutrophils/mL, 10 4Δ 0.27 ± 0.049 0.0 1.0 Eosinophils, percent Δ 0.2 ± 0.06 0.0 3.7 Eosinophils/mL, 10 4Δ 0.08 ± 0.035 0.0 0.05 T cells, percent ◊ 74.23 ± 4.31 15.8 96.7 T-helper cells, percent ◊ 46.88 ± 3.69 11.2 77.7 T-suppressor cells, percent ◊ 20.65 ± 2.14 5.7 44.7 Helper/suppressor ratio ◊ 2.78 ± 0.32 0.7 6.0 B cells, percent ◊ 3.46 ± 1.00 0.0 17.5 IgG, mcg/mL § 9.14 ± 0.82 2.1 17.7 IgA, mcg/mL § 7.63 ± 0.80 2.6 22.5 IgM, mcg/mL § 0.33 ± 0.06 0.05 1.4 Albumin, mcg/mL § 46.39 ± 3.82 13.6 84.2 Total protein, mcg/mL § 97.69 ± 5.78 43.4 171.1 BAL: bronchoalveolar lavage. * 5th percentile of the study population. • 95th percentile of the study population. Δ n = 50. ◊ n = 26. § = 46. Data from: BAL Cooperative Group. Am Rev Respir Dis 1990; 141:S169 (BAL Cooperative Group, 1990 #261). Expected values of BAL fluid constituents in healthy smokers Variable Mean ± SEM 5th percentile* 95th percentile •

BAL: bronchoalveolar lavage. * 5th percentile of the study population. • 95th percentile of the study population. Δ n = 50. ◊ n = 26. § = 46. Data from: BAL Cooperative Group. Am Rev Respir Dis 1990; 141:S169 (BAL Cooperative Group, 1990 #261). Expected values of BAL fluid constituents in healthy smokers Variable Mean ± SEM 5th percentile* 95th percentile • Percent recovery of lavagate 59.2 ± 1.4 35.9 74.9 Total cells, 10 6Δ 59.9 ± 7.3 10.5 176.0 Total cells/ml, 10 4Δ 41.8 ± 4.5 8.1 117.1 Macrophages, percent Δ 92.5 ± 1.0 79.5 99.0 Macrophages/mL, 10 4Δ 39.0 ± 4.3 7.0 108.4 Lymphocytes, percent Δ 5.2 ± 0.9 1.0 18.6 Lymphocytes/mL, 10 4Δ 1.74 ± 0.28 0.1 7.1 Neutrophils, percent Δ 1.6 ± 0.2 0.0 7.0 Neutrophils/mL, 10 4Δ 0.82 ± 0.18 0.0 3.5 Eosinophils, percent Δ 0.56 ± 0.13 0.0 3.0 Eosinophils/mL, 10 4Δ 0.28 ± 0.09 0.0 2.5 T cells, percent ◊ 69.2 ± 4.32 15.0 95.5 T-helper cells, percent ◊ 32.21 ± 2.71 9.0 65 T-suppressor cells, percent ◊ 29.2 ± 3.0 5.0 58 Helper/suppressor ratio ◊ 1.64 ± 0.29 0.30 6.1 B cells, percent ◊ 6.54 ± 1.54 0.0 28.1 IgG, mcg/mL § 10.22 ± 0.90 2.5 22.2 IgA, mcg/mL § 5.94 ± 0.53 1.06 15.4 IgM, mcg/mL § 0.227 ± 0.05 0.01 1.0 Albumin, mcg/mL § 42.92 ± 2.73 14.0 91.1 Total protein, mcg/mL § 95.39 ± 5.24 37.8 182.7 BAL: bronchoalveolar lavage. * 5th percentile of the study population. • 95th percentile of the study population. Δ n = 64. ◊ n = 29. § n = 62. Data from: BAL Cooperative Group. Am Rev Respir Dis 1990; 141:S169 (BAL Cooperative Group, 1990 #261).

©2013 UpToDate ® Print Email Expected values of BAL fluid constituents in healthy never smokers Variable Mean ± SEM 5th percentile* 95th percentile • Percent recovery of lavagate 63.4 ± 1.1 40.8 80.3 Total cells, 10 6Δ 18.1 ± 1.9 5.2 33.1 Total cells/mL, 10 4Δ 12.9 ± 2.0 3.1 35.1 Macrophages, percent Δ 85.2 ± 1.6 54.6 97.1 Macrophages/mL, 10 4Δ 9.9 ± 0.8 2.7 27.5 Lymphocytes, percent Δ 11.81 ± 1.1 1.9 34.3 Lymphocytes/mL, 10 4Δ 1.49 ± 0.25 0.2 4.9 Neutrophils, percent Δ 1.6 ± 0.7 0.0 3.1 Neutrophils/mL, 10 4Δ 1.2 ± 1.1 0.0 0.4 Eosinophils, percent Δ 0.19 ± 0.06 0.0 1.1 Eosinophils/mL, 10 4Δ 0.02 ± 0.007 0.0 0.2 T cells, percent ◊ 70.27 ± 3.56 25.6 94.9 T-helper cells, percent ◊ 44.4 ± 3.71 7.6 83.5 T-suppressor cells, percent ◊ 20.73 ± 2.17 6.6 49.4 Helper/suppressor ratio ◊ 2.61 ± 0.29 0.5 6.4 B cells, percent ◊ 3.23 ± 0.85 0.0 17.1 IgG, mcg/mL § 5.92 ± 0.48 1.6 14.5 IgA, mcg/mL § 6.22 ± 0.60 1.1 15.3 IgM, mcg/mL § 0.20 ± 0.019 0.03 0.6 Albumin, mcg/mL § 34.23 ± 1.67 15.7 59.3 Total protein, mcg/mL § 78.24 ± 4.04 39.5 140.7 BAL: bronchoalveolar lavage. * 5th percentile of the study population. • 95th percentile of the study population. Δ n = 77. ◊ n = 30. § n = 76. Data from: BAL Cooperative Group. Am Rev Respir Dis 1990; 141:S169 (BAL Cooperative Group, 1990 #261).