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©2013 UpToDate ® Print Email Bone marrow aspirate of acute lymphoblastic leukemia Bone marrow aspirate shows lymphoblasts with variable sizes, scant cytoplasm with vacuolation in a few cells, and convoluted nucleus (L2 morphology). Wright-Giesma, 100x magnification. Reproduced with permission from: Sun T. Clinical application. In: Flow Cytometry, Immunochemistry, and Molecular Genetics for Hematologic Neoplasms, 2nd ed, Lippincott Williams & Wilkins, Philadelphia 2012. Copyright © 2012 Lippincott Williams & Wilkins. file://www.lww.com