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contentuptodate· Content· item f8_59_9150

©2013 UpToDate ® Print Email BMD and bone turnover markers are independent predictors of hip fracture risk Low BMD was defined according to the WHO guidelines, ie, by a value 2.5 SD or more below the young-adult mean (T-score ≤2.5). High bone resorption was defined by CTX or free D-Pyr values higher than the upper limit (mean +2 SD) of the premenopausal range. Women with both low hip BMD and high bone resorption were at a higher risk of hip fracture than women with either low hip BMD or high bone resorption. CTX: C-telopeptide; D-Pyr: free deoxypyridinoline. Reproduced with permission from: Garnero, P, Hausherr, E, Chapuy, MC, et al. Markers of bone resorption predict hip fracture in elderly women: the EPIDOS Prospective Study. J Bone Miner Res 1996; 11:1531. Copyright ©1996 American Society for Bone and Mineral Research.