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©2013 UpToDate ® Print Email Seroprevalence of babesiosis by area, year, and time of year Region Timeframe Demographic Seroprevalence Nantucket Island August 1975 to July 1976 [1] History of tick bite or fever for ≥3 days 7.5 percent August 1975 to July 1976 [1] Residents and visitors 1.9 percent Cape Cod Summer 1984 [2] Blood donors 3.7 percent Block Island September 1990 to February 1991 [3,4] Residents 4.6 percent Biannual serosurveys at beginning of summer and in the fall of 1999 and 2000) [5] Residents 9 percent Southern Connecticut July 1999 [6] Blood donors 1.9 percent Fall 1999 [6] Blood donors 0.5 percent Year 2000 [5] Blood donors 9 percent Hartford County, Connecticut Summer and fall 1999 [6] Blood donors 0.2 to 0.5 percent Shelter Island June 1978 [7] Residents 4.4 percent October 1978 [7] Residents 6.9 percent May 1998 [8] Blood donors 4.3 percent South Fork, Long Island Fall 1984 [8] Blood donors 15.8 percent Eastern Long Island Winter 1994-95 [9] Residents 1 percent 1. Ruebush, TK, 2nd, Juranek, DD, Chisholm, ES, et al. Human babesiosis on Nantucket Island. Evidence for self-limited and subclinical infections. N Engl J Med 1977; 297:825. 2. Popovsky, MA, Lindberg, LE, Syrek, AL, Page, PL. Prevalence of Babesia antibody in a selected blood donor population. Transfusion 1988; 28:59. 3. Krause, PJ, Telford, SR, 3rd, Pollack, RJ, et al. Babesiosis: an underdiagnosed disease of children. Pediatrics 1992; 89:1045. 4. McQuiston, JH, Childs, JE, Chamberland, ME, Tabor, E. Transmission of tick-borne agents of disease by blood transfusion: a review of known and potential risks in the United States. Transfusion 2000; 40:274. 5. Krause, PJ, McKay, K, Gadbaw, J, et al. Increasing health burden of human babesiosis in endemic sites. Am J Trop Med Hyg 2003; 68:431. 6. Leiby, DA, Chung, AP, Gill, JE, et al. Demonstrable parasitemia among Connecticut blood donors with antibodies to Babesia microti. Transfusion 2005; 45:1804. 7. Filstein, MR, Benach, JL, White, DJ, et al. Serosurvey for human babesiosis in New York. J Infect Dis 1980; 141:518. 8. Linden, JV, Wong, SJ, Chu, FK, et al. Transfusion-associated transmission of babesiosis in New York State. Transfusion 2000; 40:285. 9. Hilton, E, DeVoti, J, Benach, JL, et al. Seroprevalence and seroconversion for tick-borne diseases in a high-risk population in the northeast United States. Am J Med 1999; 106:404.