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OR 150 to 200 mg/kg per day in four divided doses Maximum daily dose 10 g Ampicillin-sulbactam• 150 to 200 mg/kg (of ampicillin component) per day in four divided doses Maximum daily dose 8 g For patients with potential severe hypersensitivity to beta-lactam antibiotics (eg, penicillin, cephalosporin) Vancomycin*•

OR 6 months to 5 years: 20 mg/kg per day in two divided doses ≥5 years: 10 mg/kg once per day Maximum daily dose 500 mg Ciprofloxacin• 20 to 30 mg/kg per day in two divided doses Maximum daily dose 800 mg For patients with nonanaphylactic hypersensitivity to penicillin and cephalosporin Vancomycin*•

OR 90 to 120 mg/kg per day in three to four divided doses Maximum daily dose 8 g Meropenem• 60 to 120 mg/kg per day in three divided doses Maximum daily dose 6 g * Vancomycin is indicated in patients with moderate to severe sepsis, patients who may have concomitant meningitis, and patients from areas with an increased prevalence of clindamycin-resistant and/or methicillin-resistant Staphylococcus aureus isolates. Trough levels of 15-20 mcg/mL are suggested for severe infections. • Dosage modification for renal insufficiency is necessary. See drug information topic. Δ A third-generation cephalosporin (ceftriaxone or cefotaxime) is preferred to ampicillin sulbactam.