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Irrigation: Based on standard for each surgical procedure Dosing: Pediatric Refer to adult dosing. Dosing: Geriatric Refer to adult dosing. Dosing: Renal Impairment No dosage adjustment provided in manufacturer’s labeling. Dosing: Hepatic Impairment No dosage adjustment provided in manufacturer’s labeling. Dosage Forms: U.S. Excipient information presented when available (limited, particularly for generics); consult specific product labeling. Solution, ophthalmic [irrigation; preservative free]: Sodium chloride 0.64%, potassium chloride 0.075%, calcium chloride 0.048%, magnesium chloride 0.03%, sodium acetate 0.39%, sodium citrate 0.17% (18 mL, 500 mL) AquaLase®: Sodium chloride 0.64%, potassium chloride 0.075%, calcium chloride 0.048%, magnesium chloride 0.03%, sodium acetate 0.39%, sodium citrate 0.17% (90 mL) BSS®: Sodium chloride 0.64%, potassium chloride 0.075%, calcium chloride 0.048%, magnesium chloride 0.03%, sodium acetate 0.39%, sodium citrate 0.17% (15 mL, 30 mL, 250 mL, 500 mL) BSS Plus®: Sodium chloride 0.71%, potassium chloride 0.038%, calcium chloride 0.015%, magnesium chloride 0.02%, sodium phosphate 0.042%, sodium bicarbonate 0.21%, dextrose 0.092%, glutathione 0.018% (250 mL, 500 mL) Generic Equivalent Available: U.S. Yes Administration Not for injection or I.V. infusion. Do not use if discolored or contains a precipitate. Solution should be used when between 15°C to 25°C (59°C to 77°F). Use Irrigation solution for ophthalmic surgery: AquaLase®, BSS®: Intraocular or extraocular irrigating solution BSS Plus®: Intraocular irrigating solution Irrigation solution for eyes, ears, nose, or throat Adverse Reactions Significant >10%: Ocular: Intraocular pressure increased (11% to 12%), cataract (7% to 11%) 1% to 10%: Central nervous system: Headache (3%) Ocular: Discomfort (3% to 5%), dry eyes (3% to 5%), macular edema (4%), conjunctival hyperemia (3% to 4%), posterior capsule opacification (2% to 3%), iritis (1% to 3%), retinal hemorrhage (1% to 3%), blurred vision (1% to 2%) Contraindications Injection or I.V. infusion; use during electrosurgical procedures Warnings/Precautions

Other warnings/precautions: • Appropriate use: For use during surgical procedures with an expected duration ≤60 minutes. Metabolism/Transport Effects None known. Drug Interactions (For additional information: Launch Lexi-Interact™ Drug Interactions Program ) There are no known significant interactions. International Brand Names Balanced Salt Solution (DK, FI, GB, NZ) Use of UpToDate is subject to the Subscription and License Agreement . Topic 8800 Version 32.0 © 2013 UpToDate, Inc. All rights reserved. | Subscription and License Agreement | Release: 21.6- C21.56 Licensed to: AsanBook Dig. Med. Lib. | Support Tag: [1005-213.131.41.98-64F77B4D5B-S244013.14]