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©2013 UpToDate ® Print Email Birbeck granules This electron micrograph of a Langerhans' cell shows a number of typical Birbeck granules (arrow). (39,000 X). Electron micrograph courtesy of Dr. Dominic V. Spagnolo, Perth, Western Australia. From Warnke, RA, Weiss, LM, Chan, JK, Cleary, ML, Dorfman, RF. Tumors of the lymph nodes and spleen. Atlas of tumor pathology (electronic fascicle), Third series, fascicle 14, 1995, Washington, DC. Armed Forces Institute of Pathology.