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©2013 UpToDate ® Print Email Common locations of bone tumors Chondroblastoma favors the epiphysis in the skeletally immature patient. Round cell lesions favor the diaphysis. The majority of other lesions favor the metaphysis. Giant cell tumors will extend to the joint surface in a skeletally mature patient. Reproduced with permission from: Daffner RH. Clinical Radiology: The Essentials, 3rd Edition. Philadelphia: Lippincott Williams & Wilkins, 2007. Copyright © 2007 Lippincott Williams & Wilkins.