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©2013 UpToDate ® Print Email Brain MRI of chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) Initial T1-weighted postgadolinium brain MRI of a 48 year-old man with progressive vertigo, ataxia, and dysarthria. A) Symmetric enhancement of the pons and both cerebellar peduncles, with pattern highly suggestive of a perivascular distribution. B) Near complete resolution with corticosteroids. C) Recurrence of the same lesions without corticosteroids. Reproduced with permission from: Lefaucheur R, Bouwyn JP, Ahtoy P, Gérardin E, Derrey S, Maltête D. Teaching neuroimages: punctuate and curvilinear enhancement peppering the pons responsive to steroids. Neurology 2011; 77:e57. Copyright © 2011 Lippincott Williams & Wilkins.