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©2013 UpToDate ® Print Email Brain and spine MRI of a child with acute disseminated encephalomyelitis (ADEM) A) Axial MRI of the brain (FLAIR image) in a child with acute disseminated encephalomyelitis (ADEM) demonstrates multifocal areas of hyperintensity in both cerebral hemispheres involving cortical gray matter, centrum semiovale, and deep gray nuclei. B) Sagittal MRI of the spine (T2 image) in the same child demonstrates high signal intrinsic to the spinal cord, consistent with longitudinally extensive transverse myelitis. Courtesy of Tim Lotze, MD.