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©2013 UpToDate ® Print Email Immune globulin products available in the United States or Canada for subcutaneous and intramuscular use Trade name Licensed route(s) of administration Manufacturer (processed by) Available vial sizes (mL) Dose adjustment factor* Concentration Stabilizer concentration IgA Content (average) Hizentra ® Subcutaneous CSL Behring 5, 10, 20 1.53 20 percent L-proline 0.25M ≤50 mcg/mL Gammagard ® Liquid Subcutaneous and intravenous Baxter 10, 25, 50, 100, 200, 300 1.37 10 percent Glycine 0.25M 37 mcg/mL Gamunex ® -C Subcutaneous and intravenous Grifols 10, 25, 50, 100, 200 1.37 10 percent Glycine 0.16 to 0.24M 46 mcg/mL GamaSTAN ® S/D Intramuscular Grifols 2, 10 Not applicable 15 to 18 percent Glycine 0.21 to 0.32M Not specified Gammaked™ Subcutaneous and intravenous Grifols 10, 25, 50, 100, 200 1.37 10 percent Glycine 0.16 to 0.24M 46 mcg/mL M: mol/L * To calculate the initial weekly dose for subcutaneous administration, multiply the previous intravenous immunoglobulin dose in grams by the dose adjustment factor shown; then divide this by the number of weeks between doses (eg, three or four). Data from: US licensed product information (available online at file://dailymed.nlm.nih.gov/dailymed/about.cfm , accessed on April 26, 2012) and Health Canada licensed product monograph (available online at file://webprod3.hc-sc.gc.ca/dpd-bdpp/index-eng.jsp accessed on April 26, 2012). All preparations are in liquid form.