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contentuptodate· Content· item f30_34_31273

©2013 UpToDate ® Print Email Lymph node biopsy in Langerhans cell histiocytosis CD1a stain (A) The lesion fills and expands lymph node sinuses, and the Langerhans cells are associated with eosinophils and giant cells. Hematoxylin-eosin stain. (B) Immunostain for CD1a highlights numerous Langerhans cells. Immunochemistry with hematoxylin counterstain. Reproduced with permission from: Ioachim HL, Medeiros LJ. Dendritic cell neoplasms. In: Ioachim's Lymph Node Pathology, 4th ed, Lippincott Williams & Wilkins, Philadelphia 2009. Copyright © 2009 Lippincott Williams & Wilkins. file://www.lww.com