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contentuptodate· Content· item f15_43_16063
©2013 UpToDate ® Print Email CFTR gene Schematic representation of the CFTR gene and its encoded polypeptide. ΔF508 refers to the site of the most common mutation causing cystic fibrosis. CFTR: cystic fibrosis transmembrane conductance regulator Redrawn from Welsh, MJ, Tsui, L-C, Boat, T, Beaudet, AL. Cystic fibrosis. In: The Metabolic and Molecular Basis of Inherited Disease, Scriver, CR, Beaudet, AL, Sly, WS, et al (Eds), McGraw-Hill, New York, 1995, p. 3801.