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Maximum score 9 Adjusted stroke rate according to CHA 2 DS 2 -VASc score CHA 2 DS 2 -VASc score Patients (n = 7329) Adjusted stroke rate (percent/year) • 0 1 0 percent 1 422 1.3 percent 2 1230 2.2 percent 3 1730 3.2 percent 4 1718 4.0 percent 5 1159 6.7 percent 6 679 9.8 percent 7 294 9.6 percent 8 82 6.7 percent 9 14 15.2 percent AF: atrial fibrillation; EF: ejection fraction (as documented by echocardiography, radionuclide ventriculography, cardiac catheterization, cardiac magnetic resonance imaging, etc); LV: left ventricular; TIA: transient ischaemic attack. * Prior myocardial infarction, peripheral artery disease, aortic plaque. Actual rates of stroke in contemporary cohorts may vary from these estimates. • Based on Lip, et al. From: Camm AJ, Kirchhof P, Lip GY, et al. Guidelines for the management of atrial fibrillation: The Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC). Eur Heart J 2010; 31:2369. By permission of the European Society of Cardiology. Copyright © 2012 Oxford University Press.