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Walk the Even Hospital Database by book and chapter — the raw source passages that ground Ask, DDx, and the rest.
1 passage
©2013 UpToDate ® Print Email Children's Oncology Group neuroblastoma risk strata Risk Stage Age MYCN status DNA ploidy INPC Other Low* 1 Any Any Any Any 2a/2b Any Not amp Any Any Resection ≥50 percent 4s <365 days Not amp DI >1 FH Asymptomatic Intermediate• 2a/2b 0-12 years Not amp Any Any Biopsy or resection <50 percent 3 <547 days Not amp Any Any 3 ≥547 days - 12 years Not amp Any FH 4 <365 days Not amp Any Any 4 365 - <547 days Not amp DI >1 FH 4s <365 days Not amp Any Any Symptomatic 4s <365 days Not amp DI = 1 Any Asymptomatic or symptomatic 4s <365 days Not amp Any UH Asymptomatic or symptomatic 4s <365 days Missing Missing Missing Too sick for biopsy HighΔ 2a/2b Any Amp Any Any Any degree of resection 3 Any Amp Any Any 3 ≥547 days Not amp Any UH 4 <365 days Amp Any Any 4 365 - <547 days Amp Any Any 4 365 - <547 days Any DI = 1 Any 4 365 - <547 days Any Any UH 4 ≥547 days Any Any Any 4s <365 days Amp Any Any Asymptomatic or symptomatic INPC: International Neuroblastoma Pathology Classification; FH: favorable histology; UH: unfavorable histology; Amp: amplified; DI: DNA Index. * Low risk groups as defined in Children's Oncology Group trial ANBL00B1. • Intermediate risk group as defined in Children's Oncology Group trial ANBL0531. Δ High risk group as defined in the Children's Oncology Group trial ANBL0532.