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©2013 UpToDate ® Print Email Cryptogenic organizing pneumonia: Low power Photomicrograph of specimen from open lung biopsy in a patient with cryptogenic organizing pneumonia. Polypoid masses of granulation tissue fill the lumens of a respiratory bronchiole and alveolar ducts (right side). Adjacent alveolar interstices are broadened by a lymphoplasmacytic inflammatory infiltrate. Hematoxylin and eosin stain. Courtesy of Talmadge E King Jr, MD. Normal lung Low power photomicrograph of normal lung tissue shows open alveoli with thin, capillary- containing interstitial spaces. An artery (A) is identifiable by its thick, muscular wall; the accompanying bronchus (B) contains mucoid material and is lined by columnar respiratory epithelial cells. Courtesy of Steven E Weinberger, MD.