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Walk the Even Hospital Database by book and chapter — the raw source passages that ground Ask, DDx, and the rest.

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contentuptodate· Content· item f5_51_5950

©2013 UpToDate ® Print Email Relative cyclooxygenase-1 and cyclooxygenase-2 selectivity of nonsteroidal antiinflammatory drugs Concentrations of various nonsteroidal antiinflammatory drugs required to inhibit the activity of cyclooxygenase-1 and cyclooxygenase-2 by 50 percent (IC50) in assays of whole blood. The diagonal line indicates equivalence. Drugs plotted below the diagonal line are more potent inhibitors of cyclooxygenase-2 than of cyclooxygenase-1. 6-MNA denotes 6-methoxy-2-naphthylacetic acid. Adapted from: FitzGerald GA, Patrono C. N Engl J Med 2001; 345:433.