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©2013 UpToDate ® Print Email CT of preinvasive lesion - AAH or AIS CT of preinvasive lesion (AAH or AIS). Axial 2-mm image through the left upper lobe shows a 5-mm pure ground-glass nodule (GGN), which has remained stable for 8 years (arrow). AAH and AIS can be single or multiple. AHH: atypical adenomatous hyperplasia; AIS: adenocarcinoma in situ. Reproduced with permission from: Travis WD, Brambilla E, Noguchi M, et al. International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung Adenocarcinoma. J Thorac Oncol 2011; 6:244. Copyright © 2011 Lippincott Williams & Wilkins.