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contentuptodate· Content· item f40_59_41916

©2013 UpToDate ® Print Email Calcium channel blockers do not change mortality after acute MI A meta-analysis of controlled trials of calcium channel blockers in postinfarction patients failed to show any effect on mortality, although the agents that reduce heart rate, particularly verapamil, showed a trend toward an improved survival while nifedipine, which increases heart rate, showed a trend toward an increased mortaltiy. Data from Held PH, Yusuf S. In: Cardiovascular Pharmacology and Therapeutics, Singh BN, Dzau V, Vanhoutte PM, Woosley RL (Eds), Churchill Livingstone, New York, 1993, p. 525.