SOFA — Sepsis-related Organ Failure Assessment

Running score: 0 / 24Low mortality (<10%)

Respiration (PaO₂/FiO₂)

PaO₂/FiO₂ ratio in mmHg. The 3- and 4-point bands require mechanical ventilation (invasive or NIV).

Coagulation (platelets × 10³/µL)

Platelet count in thousand/µL.

Liver (total bilirubin mg/dL)

Serum total bilirubin in mg/dL.

Cardiovascular (MAP + vasopressors)

Doses in µg/kg/min; pick the highest-tier criterion that is met. Epinephrine treated as norepinephrine.

CNS (Glasgow Coma Score)

Use the sedation-free GCS where possible.

Renal (creatinine mg/dL OR urine output)

Use urine-output rule only when more abnormal than the creatinine band.

qSOFA: Respiratory rate ≥ 22

Component of qSOFA — flags positive when ≥ 2 of the 3 qSOFA criteria are true.

qSOFA: Altered mentation

GCS < 15 or any new altered mentation. Component of qSOFA.

qSOFA: SBP ≤ 100 mmHg

Systolic blood pressure ≤ 100 mmHg. Component of qSOFA.